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Quinapril hydrochloride

Generic name: Quinapril hydrochloride
Brand names: Accupril

Why is Quinapril hydrochloride prescribed?

Quinapril hydrochloride is used in the treatment of high blood pressure. It can be taken alone or in combination with a thiazide type of water pill such as HydroDIURIL. Quinapril hydrochloride is in a family of drugs known as "ACE inhibitors." It works by preventing a chemical in your blood called angiotensin I from converting into a more potent form that increases salt and water retention in your body. Quinapril hydrochloride also enhances blood flow throughout your blood vessels. Along with other drugs, Quinapril hydrochloride is also prescribed in the treatment of congestive heart failure.

Most important fact about Quinapril hydrochloride

You must take Quinapril hydrochloride regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Quinapril hydrochloride ; and you must continue taking it even if you are feeling well. Quinapril hydrochloride does not cure high blood pressure; it merely keeps it under control.

How should you take Quinapril hydrochloride ?

You can take Quinapril hydrochloride with or without meals.

Alcohol may increase the effect of Quinapril hydrochloride , and could cause dizziness or fainting. Avoid alcoholic beverages until you have checked with your doctor.

Take Quinapril hydrochloride exactly as prescribed, and see your doctor regularly to make sure the drug is working properly without unwanted side effects. Do not stop taking Quinapril hydrochloride without first consulting your doctor.

--If you miss a dose...

Take the forgotten dose as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never try to "catch up" by doubling the dose.

--Storage instructions...

Quinapril hydrochloride can be stored at room temperature. Protect from light.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Quinapril hydrochloride .

• More common side effects may include:
  Dizziness, headache

Why should Quinapril hydrochloride not be prescribed?

If you are sensitive to or have ever had an allergic reaction to Quinapril hydrochloride or similar drugs, such as Capoten and Vasotec, you should not take Quinapril hydrochloride . Make sure your doctor is aware of any drug reactions you have experienced.

Special warnings about Quinapril hydrochloride

If you develop swelling of the face, lips, tongue, or throat, or of your arms and legs, or have difficulty swallowing or breathing, you should contact your doctor immediately. You may need emergency treatment.

If you develop abdominal pain with or without nausea and vomiting, contact your doctor. ACE inhibitors such as Quinapril hydrochloride have been known to cause intestinal swelling.

You may feel light-headed, especially during the first few days of Quinapril hydrochloride therapy. If this occurs, notify your doctor. If you actually faint, stop taking the medication until you have consulted with your doctor.

Vomiting, diarrhea, and heavy perspiration can all deplete your body fluid; and dehydration can cause your blood pressure to drop. If this leads to light-headedness or fainting, you should check with your doctor.

Inform your doctor or dentist that you are taking Quinapril hydrochloride before undergoing surgery or anesthesia.

Do not use potassium supplements or salt substitutes containing potassium without consulting your doctor.

If you develop a sore throat, fever, or any other sign of infection, contact your doctor immediately. It could indicate a more serious illness.

If you are taking Quinapril hydrochloride , your doctor will do a complete assessment of your kidney function and will watch it closely as long as you are taking Quinapril hydrochloride .

If you notice a yellow tinge to your skin and the whites of your eyes, stop taking the drug and notify your doctor immediately. This could be a sign of liver damage.

The safety and effectiveness of Quinapril hydrochloride in children have not been established.

Possible food and drug interactions when taking Quinapril hydrochloride

If Quinapril hydrochloride is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Quinapril hydrochloride with the following:

Diuretics such as Lasix
Lithium (Eskalith, Lithobid)
Magnesium
Potassium-sparing diuretics such as Aldactone, Dyazide, and Moduretic
Potassium supplements such as Slow-K and K-Dur
Salt substitutes containing potassium
Tetracycline (Sumycin)

Special information if you are pregnant or breastfeeding

ACE inhibitors such as Quinapril hydrochloride have been shown to cause injury and even death to the unborn child when used in pregnancy during the second and third trimesters. If you are pregnant, your doctor should discontinue Quinapril hydrochloride as soon as possible. If you plan to become pregnant, make sure your doctor knows you are taking Quinapril hydrochloride . Quinapril hydrochloride appears in breast milk and could affect a nursing infant. If Quinapril hydrochloride is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.

Recommended dosage

HIGH BLOOD PRESSURE

The usual starting dose is 10 or 20 milligrams taken once a day. If you have any problems with your kidneys or if you are also taking a diuretic, your starting dose may be lower. For adults over age 65, the usual starting dose is 10 milligrams. Depending on how your blood pressure responds, your doctor may increase your dose up to a total of 80 milligrams a day taken once a day or divided into two doses.

CONGESTIVE HEART FAILURE

The usual starting dose is 5 milligrams taken twice a day. Your doctor may increase the dose from week to week, up to as much as 20 to 40 milligrams daily, divided into 2 equal doses. If you have kidney problems, the dosage will be lower.

Overdosage

Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

A severe drop in blood pressure is the primary sign of an Quinapril hydrochloride overdose.